SOS-CHROMOTEST

The SOS-Chromotest kit is based on a novel genetically engineered E. coli, licensed from Institute Pasteur, which measures the primary response of a cell to genotoxic damage. In just a few hours, the kit provides a clear, completely objective measurement of the genotoxicity of a sample by a simple visual appreciation of the colour obtained or by spectrophotometry using a microplate reader. The SOS-Chromotest analyses are highly agreeable with the Salmonella Ames test.

The SOS-Chromotest kit has been in use since 1982, has been evaluated by hundreds of compounds and cited over 150 publications.

A single SOS-Chromotest kit can be used for a total of 96 unit tests. These tests must include standards and controls (using at least 16 units). Thus, a single kit can screen 80 samples for yes/no responses.

For quantitative measurements, it is necessary to allow for an adequate range of sample dilutions, and replicates thus testing five to ten samples with each kit.

Features:

• User friendly.
• Sensitive and reliable.
• Rapid (under 4 hours).
• Low cost.
• Contains all necessary materials to perform the assay.

Applications:

• Testing of effluents for possible mutagenic or carcinogenic genotoxic compounds, evaluation of potential genotoxicity.
• Convenient research and technical tool.